Platelet-rich fibrin (PRF) Dental Treatment Promotes Healing and Regeneration
Our bodies are equipped with many mechanisms to heal and regenerate damaged tissues. Among these, platelets are a true powerhouse, helping with the formation of blood clots in damaged tissues and regulating several healing processes, including proliferation, angiogenesis, and migration of cells. At Holistic Dental Centers in Cary and Cornelius, NC, we are committed to ensuring that oral surgical procedures are done in a way that minimizes the trauma and promotes rapid recovery. One way we can do this is through the use of platelet-rich fibrin (PRF).
Platelet-rich fibrin treatment explained

Platelet-rich fibrin is a treatment performed using your blood to take advantage of your body’s natural healing potential. After taking a small blood sample (similar to what you’d have done at your annual physical exam), the blood is spun extremely rapidly in a centrifuge machine to create a membrane containing a concentrated source of platelets. That can then be placed strategically in treatment areas where healthy regeneration of tissues is needed. Platelets include various growth factors that attract stem cells to injured tissues, stimulating several healing responses in the body, including the formation of new capillaries to promote healthy blood flow. Platelet-rich fibrin is a biocompatible treatment option that does not induce inflammation or have the potential for allergic reactions since it is created from your blood.
Uses of platelet-rich fibrin in dentistry
Platelet-rich fibrin is a versatile treatment used for both soft and hard tissue healing and regeneration. It is a terrific addition to many dental treatments that require cutting or stimulating the growth of new tissues, such as:
- Periodontal surgery
- Placement of dental implants to attract bone-forming cells
- Bone or gum grafting
- Bone cavitation surgery
- After surgery for oral cancer
- Endodontic therapy
- …and more
At Holistic Dental Centers, PRF is just one of many treatments that we offer to improve your oral health without sacrificing your overall wellness. Our holistic dental team will help you understand whether platelet-rich fibrin therapy is a good option for your specific needs and answer any questions about the procedure. To schedule your appointment at our Cary office, call (919) 865-0700, or you can reach our Cornelius office at (704) 765-3150 .

Dr. Carl McMillan
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Dr. Carl McMillan is a distinguished holistic dentist with over 20 years of experience. A Medical University of South Carolina's College of Dental Medicine graduate, he founded Holistic Dental Centers to offer safe, biological dental care in North Carolina. Dr. McMillan is a charter member of the International Academy of Mercury Free Dentists and a past president of the International Academy of Oral Medicine and Toxicology. His commitment to patient education and holistic care reflects his dedication to evidence-based, harm-free dental practices. Known for treating every patient with respect and care, Dr. McMillan is a trusted leader in his field.

Dr. Luis Crespo
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Dr. Luis Crespo, a holistic dentist with 17 years of experience, has profoundly impacted underserved communities worldwide, from Guatemala to Tibet. He earned his Doctorate of Dental Surgery from West Virginia University in 2000 and is a member of the International Academy of Oral Medicine and Toxicology. Dr. Crespo integrates his holistic health and nutrition expertise into his practice, emphasizing the connection between oral health and overall well-being. His bilingual skills and commitment to educating patients and promoting early dental care reflect his dedication to both public health and preventive medicine.
